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J Am Soc Nephrol (2019) 30(10):182540

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Specifically, in the absence of an orthosteric ligand, compound 2 displayed a strong partial agonism in cAMP response (80% Emax of GLP-1), a weak partial agonism in pERK1/2 and no detectable calcium mobilization response 29,30

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Nutrient stimulation of GIP secretion has also been reviewed here (Pais et al., 2016

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