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J Endocrinol 1988

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It is well known that HFD-induced obesity promotes low-grade hypothalamic inflammation, causing deregulation of central mechanisms that control energy homeostasis 59 , and both physical exercise and some pharmacotherapies have been shown to improve systemic metabolism by attenuating hypothalamic inflammation 60,61

Laboratory evaluation included C-reactive protein (CRP), STAT3, and TGF-1 measurement

May 2024: The judge presiding over MDL 3094, the honorable Gene E.K

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