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This triple-receptor mechanism distinguishes retatrutide from currently approved medicines such as semaglutide (a GLP-1 receptor agonist) or tirzepatide (a dual GIP/GLP-1 agonist)

We saw no significant difference in CCKAR or CCKBR expression in response to glucose in either mouse or human islets (Fig

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Graham GJ, Handel TM, Proudfoot A

By understanding this immune response, we can develop better prevention strategies