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10.3233/JAD-180688 J

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USA 112 , 1373513740 (2015)

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Discussion In the current study, SUN treatment protocol used to develop cardiotoxicity is confirmed by increasing heart weight, cardiac index and cardiotoxicity enzymatic indices, LDH and CK-MB, as well as severe histopathological changes which are manifested as scattered chronic inflammatory cells with focal fragmentation of myocardial fibers and loss of nuclei