Within the PB, the CGRP-positive cells are essential in food intake regulation and are involved in GLP-1related effects on BW (31, 91)
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This unique presentation of both NAWE and TIND in a single patient following GLP-1 agonist use warrants careful consideration of the potential central and peripheral neurological sequelae of these increasingly prevalent medications and emphasizes the need for heightened clinical awareness and appropriate monitoring strategies
Future studies should also explore the potential of emerging therapies, such as dual and triple agonists (e.g., tirzepatide and retatrutide), which have shown even greater efficacy in weight loss [20, 21]
We always recommend that you speak with your OB-GYN or midwife before adding any new supplement to your routine
These approaches focus on addressing the underlying causes of cramping, particularly hydration and electrolyte balance