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Janus kinase (JAK) inhibitors represent newer targeted synthetic DMARDs with demonstrated efficacy, though they carry boxed warnings regarding serious infections, malignancy, major adverse cardiovascular events, and thrombosis
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Originally approved for type 2 diabetes, the diabetes drug Mounjaro not only treats diabetes but also aids in weight control, leading to its off-label use for obesity
Obviously youll lose substantial muscle mass if you cut calories while not resistance training or eating enough protein
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