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That's a meaningful body of circumstantial evidence, but it's not the same as clinical proof of efficacy in humans

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Cell Mol Neurobiol 33(3):347357 Matsuzaki H, Tamatani M, Mitsuda N, Namikawa K, Kiyama H, Miyake SI, Tohyama M (1999) Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons

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& Awad, E

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For example, a small pilot study might suggest benefits, but without larger, randomized controlled trials, these results are not reliable

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J Biol Chem 261: 11880-11889, 1986

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