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For each eligible study, two authors (MM and AN) independently extracted data, which was then reviewed by a third author (JV) using a piloted spreadsheet, in accordance with Cochrane Collaboration guidelines ( Where relevant data were missing, attempts were made to contact corresponding authors

To realize this vision, future research maybe focus on standardizing the measurement of eryptosis in clinical settings, validating its role as a predictive biomarker, and conducting well-designed clinical trials to evaluate the efficacy and safety of novel anti-eryptotic agents

Variable Absorption : Oral administration may result in inconsistent bioavailability, affecting effectiveness or tolerability

A study by Marmar et al

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However, other studies show that zinc can inhibit NET release and degranulation, possibly by reducing citrullinated histone H3 levels [163]