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PubChem Compound Summary for CID 45382195, Thymosin Beta 4
Repairs DNA naturally
10.1111/jgh.13787 148 O'bryantS
Since superoxide anion cannot diffuse across the inner mitochondrial membrane it remains in the matrix which allows it to react with Fe-S groups in mitochondrial proteins resulting in the liberation of ferrous (Fe 2+ ) iron
The Phase 1b/2a clinical trial (NCT04445831), which was sponsored by AC Immune SA (clinical-stage biopharmaceutical company), examined the safety, tolerability, and immunogenicity of two tau-targeted liposomal vaccines, namely ACI-35.030 and JACI-35.054, in the early stages of AD