Journal of the American Medical Association , 294(1), 97104
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The REDEFINE Phase 3 program directly addressed this, showing CagriSema achieved 20.4% weight loss versus lesser results with semaglutide alone, cagrilintide alone, and placebo
Another SOAT gene, SOAT1, encodes a protein that is also involved in the regulation of intracellular cholesterol concentrations
Supplementation may help lower this risk