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Complementary to this, supervised pelvic floor muscle exercises have been shown to reduce chronic pelvic pain in women with endometriosis and are clinically used to address abdominal distension or endo belly by improving tissue mobility, breathing mechanics, and nervous system sensitization

Because ROS can mediate signal transduction through mechanisms such as oxidation of cysteine residues in proteins, modulation of phosphorylation networks, and regulation of transcription factor activity, they are increasingly recognized not merely as metabolic byproducts but also as redox-sensitive signaling mediators that coordinate cellular responses ( In high-grade serous ovarian cancer (HGSOC), the axis of oxidative stress and ROS has been discussed as a pathophysiological mechanism across multiple stages, including tumor initiation, progression, metastasis, and therapeutic resistance

I was also fortunate to work on both large clinical trials and small studies involving precise physiological measurements

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Diabetes Care 27 , 155161 (2004)