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A trial of alogliptin (EXAMINE) was performed in 5380 patients with an acute coronary syndrome

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In addition, the FLOW clinical trial reported a high granularity of data, and this enabled accurate modeling of both risk factors and resource use

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The histidine imidazole nitrogen, the glycine -amino group, and the glycine carbonyl oxygen coordinate to the Cu ion in a square-planar geometry, creating a stable chelate with a dissociation constant in the femtomolar range

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