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These injectable biomaterials could potentially replace the nucleus pulposus while promoting surrounding tissue repair
Due to cardiomyocytes requiring massive energy demands, they are rich in mitochondria standing out from the rest of the cell type [15, 16], which makes them very sensitive to oxidative stress damage
By wrapping the glutathione molecule in this protective layer, we allow it to pass through the digestive system safely
For example, the rapid pyroptotic cell death of SARS-CoV-2-infected blood monocytes or lung-resident macrophages prevents the virus from completing its reproductive cycle ( However, DAMPs-mediated signalling can also generate detrimental effects, particularly when a massive release of pro-inflammatory DAMPs from dying cells causes more cells to die: a situation that strongly contributes to the CD4+ T cell depletion in patients infected with HIV-1 (63, 64), reviewed in (65)
