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[1] In the SURMOUNT-1 clinical trial, higher doses in non-diabetic adults demonstrated significant weight loss, with participants losing approximately 15-20% of body weight over 72 weeks
The NHS confirms that taking up to 2mg (2000 micrograms) daily is unlikely to cause harm, with no established upper limit in the UK
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Excess mitochondrial ROS production, causes cellular oxidative stress, sustains mitochondrial dysfunction and ROS production and perpetuates inflammation (Chang et al., 2021)
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American Journal of Epidemiology, 163 (2), 142150
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