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Two groups of individuals were assessed: those receiving oral semaglutide and those taking other oral glucose-lowering therapies
Unlike GLP-1, GIP can promote glucagon secretion in normal and hypoglycemic states, and inhibit it in hyperglycemia, thus acting as a bifunctional hormone to maintain blood glucose homeostasis
Most of the studies done so far on semaglutide use have not included women who have been trying to get pregnant or are pregnant
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In some cases, dose adjustment of tirzepatide may be necessary, though this should be balanced against glycemic control and weight management goals
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