Continuation of semaglutide resulted in a further 7.9% reduction in body weight from their week 20 weight, whereas the placebo group regained 6.9% [92]
So I dont think this aspect is a concern
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4b) with similar potency but lower efficacy (~10%) than glucagon (ESM Table 4)
Another study did not show any differences with the hormone combination on glucose and food intake reduction or enhanced energy expenditure but used far lower doses of GLP-1 (1 pmol/kg/min) and glucagon (0.86 pmol/kg/min) (68)
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