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Proc Natl Acad Sci USA (2011) 108:62527
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Monitoring Requirements in Liver-Compromised Patients Baseline laboratory assessment should include a comprehensive metabolic panel (ALT, AST, alkaline phosphatase, total and direct bilirubin, albumin), complete blood count with platelets, and coagulation studies (INR/PT)
More direct evidence for GLP-1 modulating dopamine transmission comes from a study showing that a GLP-1 agonist also reduced phasic dopamine response in the VTA in rats (Konanur et al., 2020)
Additionally, Wegovy delays gastric emptying, which may affect the absorption of oral medications, particularly those with a narrow therapeutic index (such as warfarin, requiring INR monitoring)
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