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The TRIUMPH-4 trial protocol provides the best reference for effective dosing : Weeks 1-4: 2 mg once weekly (starting dose) Weeks 5-8: 4 mg once weekly Weeks 9-12: 6 mg once weekly Weeks 13-16: 8 mg once weekly Week 17+: 9 mg or 12 mg once weekly (maintenance dose) The escalation happens every 4 weeks, which is slightly faster than many tirzepatide protocols
Ive already lost 22 lbs and feel more in control of my appetite than ever
2024;16:e13547
Eli Lilly's once-daily oral GLP-1, Orforglipron , is becoming a formidable rival by assisting patients in maintaining their hard-won weight loss following injectable treatments
This additive effect suggests the compound enhances the benefits of physical training
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