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Notably, weight reduction was dose-dependent and progressive, with participants continuing to lose weight throughout the study period, suggesting potential for even greater efficacy with extended treatment duration

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Glucagon Receptor Activation: Stimulates thermogenesis, elevates resting energy expenditure, and promotes hepatic lipid oxidation

Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction