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Sample HIIT Routine: Warm-up: 5 minutes of light cardio Intervals: 30 seconds of high-intensity exercises (burpees, jumping jacks, sprints) followed by 30 seconds of rest Repeat for 15-20 minutes Cooldown: 5 minutes of stretching 4

FIGURE 1 DSIP-CBBBP reduces anxiety or depressive-like states Figure 2 delineates the effects of different treatments on locomotor activity in mice within an insomnia model, as assessed by the open field test