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These agents help reduce appetite and delay gastric emptying, leading to reduced food intake useful for people with obesity

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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the First-in-Class GLP-1 and Amylin Receptor Agonist, Amycretin: A First-in-Human, Phase 1, Double-Blind, Randomised, Placebo-Controlled Trial

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Aggregation changes the apparent molecular weight and can reduce bioactivity