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26 PARPs catalyze reversible ADP-ribosylation of macromolecular targets including proteins, DNA and RNA, utilizing NAD + as a cofactor to provide monomer or polymers of ADP-ribose nucleotide
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The cagrilintide dosage with retatrutide would theoretically combine amylin pathway activation with this triple-agonist approach
10.1016/j.ajhg.2018.12.021 Am
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