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PEX-168 is a new agent of long-acting GLP-1R agonist, which is molecularly modified from EX via amino acid modification and PEGylation (119), the first GLP-1R agonist modified by PEG to achieve long-term pharmacological action (120, 121)

This makes dosage accuracy and sustainability critically important in the long term

Current clinical evidence suggests that starting GLP-1 therapy in gastroparesis requires careful medical evaluation and baseline gastric function assessment, not automatic exclusion from treatment

PubMed laboratory research record [PMID: 40796132] PubMed record related to this compound for laboratory literature review

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pylori from the digestive tract may increase GLP-1 levels