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Amyloid -based therapy for Alzheimers disease: challenges, successes and future

Gene expression analysis Total RNA from cecal tissue was isolated using the RNeasy Mini kit (Qiagen, Valencia, CA)

Choi JH et al

These can play havoc with brain function as they build up and are a contributor to Alzheimers disease

This interplay highlights that dysregulated PCD is likely a key contributor to the pathogenesis of DOR, rather than a singular causative factor

The Phase 3 TRIUMPH-1 results released in May 2026 told a similar story: the common side effects were nausea, diarrhoea, constipation, vomiting, an altered skin sensation called dysesthesia, and urinary and respiratory infections