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Both classes cause similar gastrointestinal effects (nausea, vomiting, constipation)
And eating too quickly or in too-large portions overwhelms a digestive system that is already operating at a slower pace due to the medication delayed gastric emptying effect
Nature 518 , 197206 (2015)
This inactivates GLP-1 as an intact N-terminal end is required for binding to its receptor [13]
Cytogenetics and Cell Genetics
While studies are currently exploring the possibilities of preventing these side effects, there are currently no GLP-1 drugs on the market that do not have the potential to cause these side effects
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