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Early human trials provide signals of target engagement, such as preserved cerebral glucose metabolism, altered inflammatory biomarkers, and slowed brain atrophy, although clinical outcomes to date remain mixed and trials in rarer disorders are sparse
Glutathione is a powerful anti-oxidant that helps to protect cells from damage caused by free radicals and toxins
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These are similar to the licensed versions but are not FDA-approved and carry risks
Extracellular hydrolysis of ATP to adenosine is catalyzed by extracellular soluble 5-nucleotidases
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