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Frequency depends on your individual needs, but many patients benefit from weekly or bi-weekly treatments initially, then monthly for maintenance

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Abbreviations ABC ATP-binding cassette ABCA1 ATP-binding cassette transporter A1 GLP-1 glucagon-like peptide-1 GSIS glucose-stimulated insulin secretion HDL high-density lipoprotein HDL-C high-density lipoprotein cholesterol H&E Hematoxylin and eosin IHC immunohistochemical IP immunoprecipitation LDL low-density lipoprotein LSG laparoscopic sleeve gastrectomy LXR liver X receptor OGTT oral glucose tolerance test PARP poly ADP-ribose polymerase RCT reverse cholesterol transport RYGB Roux-en-Y gastric bypass STZ streptozotocin TC total cholesterol TG total triglyceride T2DM type 2 diabetes

The Oxford 2011 levels of evidence

The medication is injected by the patient subcutaneously, typically in the abdomen, thigh, or upper arm