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For example, the senescence of cardiac endothelial cells may exacerbate myocardial ischemia and heart failure

Hydroxocobalamin may also be given intravenously in certain scenarios (for example, 5 g IV for acute cyanide poisoning antidote therapy), but such high-dose use is in emergency settings and distinct from routine deficiency treatment

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One key group includes individuals with pernicious anemia, an autoimmune condition that affects the bodys ability to absorb vitamin B12 from food

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