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People who are unable to absorb vitamin B-12 properly may have pernicious anemia, which is a type of anemia characterized by a lack of intrinsic factor

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[PubMed | ClinicalTrials.gov | DOI] Rubino D, Abrahamsson N, Davies M, et al

Compound class: small-molecule NNMT inhibitor

At the same dose, a 74 kg participant had about 1.4 times the exposure of a 110 kg reference, while a 143 kg participant had about 0.8 times. Weight alone does not set the dose, but it helps explain why the trial mean transfers poorly to bodies outside the studied range

Common tests include: Serum vitamin B12 the baseline measurement, though it can be normal even in early or borderline deficiency