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This study showed effects at very low concentrations (picomolar to nanomolar), which is encouraging for topical application

One of the most commonly reported side effects across GLP-1 types is nausea, a sick-to-the-stomach feeling that often creates an urge to vomit, and a loss of appetite

This raises significant patient safety concerns

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The elevated CHAC1 expression in LUAD promotes tumor proliferation and metastasis by enhancing glycolysis, lactate production, and ATP generation through regulation of pyruvate kinase M2 (PKM2)

H., Lee, B