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Patients often report reduced food cravings and decreased interest in previously preferred foods, which may reflect altered reward processing

In both published phase 3 trials of CagriSema there was noticeable worsening of mood based on PHQ-9 scores and increased reports of suicidal ideation during both trials

Effect of diabetes on progression of coronary atherosclerosis and arterial remodeling: a pooled analysis of 5 intravascular ultrasound trials

It makes more sense when you tie it to the gut barrier and immune reactions

We cant say that GLP-1s are actually causing these symptoms, says Neil K

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