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This medicine is only one part of a treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake and weight reduction
Reconstituted solutions are stable for 7 days when stored refrigerated, allowing for multiple uses from a single preparation
What is missing There is no published human pharmacokinetic study of subcutaneous AOD-9604, no published human topical or intranasal exposure data, no Phase 3 efficacy trial, no long-term safety data beyond 24 weeks, and no published human cartilage or joint outcome data
Hydroxocobalamin lasts longer, meaning you might need fewer shots
Supports neurotransmitter synthesis, is anti-inflammatory, and is especially useful for mood disorders, depression, dementia, PMS, skin disorders, and neuropathy
This position is supported by the NICE Guideline and at the end of 2025 we launched our freely accessible Pernicious Anaemia and B12 Deficiency education programme to the NHS community
