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At the genomic level, Epitalon modulated the expression of key circadian rhythm genes: Clock expression in leukocytes decreased 1.8-fold, Cry2 expression doubled, and Csnk1e expression in lymphocytes decreased by 2.1-fold, all with statistical significance
Miras AD, Prez-Pevida B, Aldhwayan M, Kamocka A, McGlone ER, Al-Najim W, et al
Copper Concerns The amount of copper absorbed through topical GHK-Cu is extremely low
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Antibiotics: conventional therapy and natural compounds with antibacterial activitya Pharmaco-toxicological screening
GHK-Cu and Infection-Related Readouts in Wound Contexts Mouse and clinical datasets point to a possible reduction in inflammatory proteases (for example, MMP-2/9) and cytokines (such as TNF-) in wounds exposed to GHK-Cu, aligning with lower observed infection rates in comparative ulcer care cohorts
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