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In order to reduce the incidence of injection site reactions, it is recommended to rotate the site of injection to different areas of the abdomen

This phase is marked by the onset of seizures, secondary to excitotoxic edema, cytokine accumulation, and more serious mitochondrial dysfunction

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NSAIDs primarily reduce inflammation by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), which are responsible for the production of prostaglandins, which are involved in the inflammatory response, including the promotion of pain, fever, and tissue damage