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Current Phase III trials, including the TRIUMPH studies, are assessing the long-term safety and efficacy of retatrutide in various patient groups

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Excessive differentiation of preadipocytes into mature adipocytes increases adipocyte number and size, ultimately leading to obesity

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However, there are lifestyle-related impacts to glutathione IV therapy that makes it less preferable for some patient populations who can benefit most from the compound, which makes it less convenient than alternatives like oral supplementation