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[2] [5] Understanding the realistic timeline and expected outcomes with GLP-1 therapy is crucial for patient satisfaction and adherence
The article points to people with elevated fasting glucose, significant insulin resistance and preserved pancreatic beta-cell function, the profile where metformin's insulin-sensitizing action has something to work on
doi: 10.3389/fphar.2021.627533 Goldstein, A
Cagrilintide shows greater potency and a longer half-life (approximately 7 days) than earlier amylin analogs like Pramlintide, which is why its generating attention in the metabolic optimization space
Its also important to keep fat intake low, she advised GLP-1 medications already slow stomach emptying and fat can slow it even further, which may worsen nausea
However, there is also no cogent reason to avoid the combination, and the different mechanisms of retinol and peptides for skin care and anti-aging may complement their effects
