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In the Methods, we explain why we take the multiplier, S , of the V max values of GCL and GPX to have the following dependence on estradiol, E 2: Thus, since male E 2 is 0.09 nM [26] , S = 1 for the male

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5.0 Pharmacological properties 5.1 Mechanism of Action/ Pharmacodynamic properties Glutathione is an extremely important cell protectant which directly quenches reactive hydroxyl free radicals, other oxygen-centered free radicals, and radical centers on DNA and other biomolecules

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