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GPX2, a direct target of p63, inhibits oxidative stress-induced apoptosis in a p53-dependent manner
There is also a condition called pernicious anaemia where your immune system prevents the cells in your stomach and gut from absorbing B12 from your food
Thiazolidinedione compounds, clinically used as drugs for treating type 2 diabetes, have been found to selectively inhibit ACSL4, thereby inhibiting ferroptosis [125]
For a novel compound like 5-amino-1MQ, microdosing could be an appropriate strategy, as it may provide insights into the compound's metabolism, biological activity, and safety profile
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