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Interestingly, GI adverse events and GLP-1 RA discontinuations were more common in participants not treated with metformin, which may represent increased susceptibility of this group to gut-related adverse events, resulting in intolerance to metformin previously as well as to GLP-1 RAs in the trials

After adding bacteriostatic water, allow the vial to sit undisturbed for 6090 seconds gentle swirling (not shaking) is acceptable only if powder remains undissolved after this period

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