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Sleep quality and duration profoundly affect hormonal regulation, including GLP-1 function
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Recent data from animal models suggest that some cardioprotective and vasodilatory actions of GLP-1(736) are independent of the known GLP-1 receptor and are mediated, at least in part, by its metabolite GLP-1(936) [16]
Additional oral supplementation with polypodium leucotomos extract (PLE) at 480 mg twice daily can be helpful (anecdotal evidence, unpublished)
Because appetite and thirst signals may shift during GLP-1 use, some people simply drink less without realizing it
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