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In rodent models, Dihexa at 5mg/kg orally for 7 days increased hippocampal synapse formation by 42% compared to vehicle controls, while Cerebrolysin required intravenous administration at 2.5ml/kg daily to achieve comparable synaptogenesis

Protein J

doi:10.1016/j.apnu.2017.11.015 Zamorski MA, Albucher RC

A patient with a serious non-healing musculoskeletal injury, conventional options exhausted, full informed consent, and ideally enrolment in a registered investigational protocol with structured safety monitoring

Delta waves are the slowest brain waves, characteristic of deep sleep

The n=8 endocrine study was also too small and short-term to establish safety [14]