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Rodriguez-Iturbe B, Vaziri ND, Herrera-Acosta J, Johnson RJ

[16] Although cyanocobalamin lacks a defined upper-toxicity threshold due to its water solubility and renal elimination, exceptionally high cumulative doses have been temporally associated with acneiform eruptions, altered potassium homeostasis, and theoretical thrombotic risk, emphasizing the importance of evidence-based dosing

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Finally, compared to the R group, LC patients had 49 reduced but 111 increased metabolites ( Figure 2J )

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Cap-dependent translation is frequently repressed during mitosis and the ODC1 mRNA contains an internal ribosome entry site (IRES) that allows the mRNA to be translated under these conditions