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However, endogenous GLP-1 has a short half-life ( t = 23 min) and is therefore not well suited for the treatment of T2DM [11]
Managing potential side effects To minimize the risk of side effects, doses are started low and increased gradually to allow your body time to get used to the medication
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Consult a doctor if it becomes severe
Most clinicians discontinue DPP-4 inhibitors when starting semaglutide
This natural presence suggests the synthetic version is essentially supplementing something your body already recognizes and uses
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