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The top dose produced 20.9% average weight loss over 72 weeks and 20.2% in a direct comparison with semaglutides 13.7%. Its second receptor, GIP, separates tirzepatide from approved single-receptor GLP-1 drugs and helps explain the larger population-level weight loss. That 20.9% came from participants averaging about 105 kg at a BMI of 38, most of whom were sedentary
Zanardi R, Smeraldi E
"L-carnitine and muscle cramps in cirrhosis." Clin Gastroenterol Hepatol 2015
The most popular peptides are the GLP-1 versions initially used for weight loss, and the BPC-157 (body protection compound) and TB (thymosin beta) groups used for tissue repair
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