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Similar content being viewed by others Background Drugs that inhibit dipeptidyl peptidase-4 (DPP-4) are conventionally regarded as incretin-based agents that enhance the actions of endogenous gastrointestinal hormones (glucose-like peptide-1 [GLP-1] and glucose-dependent insulinotropic polypeptide) to promote the release of insulin from the pancreas [1, 2]
This dual activation means that tirzepatide works by imitating hormones that naturally regulate appetite and blood sugar levels
N Engl J Med 376(23):23002302
Tirzepatide Drugs
This is why dopamine is so important for cognitive functions, like planning and decision-making
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