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In particular, several previously highlighted genes, including ANXA1 and RAN , showed directionally consistent L-serineassociated trends along the trajectories in this sensitivity analysis (Supplementary Fig

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Intra-Brain Distribution After crossing the BBB via specific transporter, a drug, prodrug or nanocarrier can distribute from the brain ISF into the brain parenchymal cells via the same transporter expressed at the cellular membrane followed by the release of parent drug (in case of prodrugs and nanocarriers) or binding to the cell constituents, e.g

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