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doi: 10.1001/jama.2019.2942 25 ChristakoudiSTsilidisKKEvangelouERiboliE

References/Citations Australian Government Department of Health and Aged Care (2022) Body mass index (BMI) and waist measurement, Australian Government Department of Health and Aged Care

564 HO-1 and GPX4 were downregulated due to Nrf2 defects in astrocytes, leading to increased mitochondrial fragmentation, DNA oxidation, and lipid peroxidation in mouse astrocytes, 564 suggesting that Nrf2 deficiency promotes ferroptosis in astrocytes in AD mice

It could help to determine if a novel drug is hitting the right targets and to decide what is the optimal dose, he said

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