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The following facts have been proven or are currently being discussed: Vitamin B1 (thiamine) does not have a direct effect on the skin, but its involvement in blood formation ensures rosy skin with good blood circulation Vitamin B2 (riboflavin) is important for keratinocytes and thus the skin barrier due to its positive effect on the fast-growing cells Niacin (vitamin B3) is an important vitamin for the protein metabolism, which is visible in the skin

Because B12 is a water-soluble vitamin, excess is generally excreted in urine, but that doesnt mean unlimited dosing is appropriate

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The injections are typically administered intramuscularly and are known to provide quicker relief from symptoms of B12 deficiency compared to oral supplements

This finding has implications for functional GI disorders, though it remains preclinical 10