MASH (metabolic dysfunction-associated steatohepatitis) is a progressive liver disease characterized by fat accumulation, inflammation, and fibrosis
Simultaneously, the medication causes intense gastric paralysis, leading to severe nausea, vomiting, and dehydration that stresses your kidneys and electrolyte balance
10.3390/ijms23095037 100 KoranyM
Dahl K, Brooks A, Almazedi F, Hoff ST, Boschini C, Baekdal TA (2021) Oral semaglutide improves postprandial glucose and lipid metabolism, and delays gastric emptying, in subjects with type 2 diabetes
Other patients also experienced clinical improvements, including a 6 year old boy with severe diabetes, ketosis (accumulation of ketones, a term first used by the German chemist Leopold Gmelin - figure 5), heavy glycosuria and malnutrition (de Levia, Brugus, de Leiva-Prez)
Other GLP-1 RAs, showed neutral effects