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Figure 1 Pharmacological treatment of type 2 diabetes Figure 2 Insulin therapy for type 2 diabetes Metformin is recommended for the prevention of type 2 diabetes in adults with prediabetes and in women with a history of gestational diabetes

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Reversible In many cases, filler can be adjusted or dissolved if needed

Berberine also reduces apoptosis by modulating the PI3K/Akt and p38-MAPK pathways (Han et al., 2023)

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